Human Liver S9 Fraction-50 Donors (0.5 mL) -1 vial

Species : Human Description: Pooled Human Liver S9 Fractions provide a fully characterized, relevant, reliable and reproducible in vitro tool Pooled Liver S9 Fractions from pools of 50 donors gives an accurate and economic method of deriving a population representation that may be sed to describe the metabolic profile of a drug or drug candidate in high-throughput assays as well as the following other uses:Conduct studies of metabolic stability (% of original drug remaining over time)Identify which cytochrome P450 (CYP) enzymes oxidize a drug candidate and which UDP-glucuronosyltransferase (UGT) enzymes are responsible for glucuronidationIdentify, quantify and characterize drug metabolitesDescribe a drug’s metabolic pathwaysIdentify inhibition of cytochrome P450 (CYP) enzymesand directly supplied to your lab by Gentaur's warehouse.