Human Cardiac Fibroblasts-Fetal Atrial -1 vial
Species : Human
Description: Cardiac fibroblasts (CF) provide structural support for cardiac myocytes and are responsible for extracellular matrix synthesis in the heart during growth and pathophysiological conditions CF are an important cellular component of myocardial responses to injury and the source of paracrine growth factors Their proliferation and synthesis of matrix is essential for scar formation at sites of myocardial infarction and cardiac fibrosis CF cultures have been widely used as a model to study the cardiac matrix remodeling by physiological (exercise) and pathological (hypertension) stressors CF also has been found to form electric coupling with myocytes through gap junctions exerting electrotonic influences on the cells These electronic couplings are suggested to play an important role in genesis of complex fractionated atrial electrogram sites and thus are a perfect model for study of atrial fibrillationHCF-fa from AcceGen Research Laboratories are isolated from the human fetal atrium HCF-fa are cryopreserved at secondary culture and delivered frozen Each vial contains >5×10^5 cells in 1 ml volume HCF-fa are characterized by immunofluorescence with antibody specific to fibronectin HCF-fa are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi HCF-fa are guaranteed to further expand for 15 population doublings under the conditions provided by AcceGen Research Laboratoriesand directly supplied to your lab by Gentaur's warehouse.